Just a thought but it would depend on the type of snake. I was hit by a copperhead on my Muck Woody Armour boots & I felt it but it wasn't a hard hit. I'm sure a bigger, stronger snake like a cotton mouth or a rattler would go right through a pair of neos or rubber. The stronger snakes hit pretty hard from what I've been told. I wear the Lacrosse aero elite snake boots now & love them!