I've tried to follow some of the more popular routines out there of shooting x number of rounds then cleaning, repeat, repeat, repeat.
Never could tell that it made a difference.
Now, I normally just shoot with some generally decent loads to form brass and see what kind of potential it has. By the time I get all that done I've usually got over 100 rounds through the barrel. I'll give it a good scrubbing then, removing all the copper, then call it quits and won't clean again until I start losing accuracy.