By E-scouting, I am assuming that you are referring to using a mapping app. If so, there are a number of things I look at. I want to use a mapping source (OnX, Basemap, etc.) that provides as much information as possible on such things as land status, road and trail systems, topographical views, aerial satellite views, 3D views. etc.
On the "macro" scale, I want to identify the boundaries of the area/property I will be hunting. If it is a large public area like a National Forest, or similar, I try to narrow down things by looking at the habitat characteristics that might be conducive to holding turkeys. Basic stuff like roosting habitat, water availability, nearby farming/agriculture/artificial food plots, etc. Of course, the relative value of those factors can vary a lot based on where you are hunting.
On smaller properties (and assuming other hunters are hunting there), I tend to look for less accessible areas that might be difficult to access from the property access points. However, one "wild card" that often exists in that strategy is understanding that hunters might be able to access those same places from surrounding holdings (it is always a bummer when you work your tail off to get to an isolated spot only to find out the property owner across the boundary is letting hunters go in from across his land). The point being that it is also a good idea to contemplate the access issue from the surrounding properties, as well.
Personally, I really enjoy "E-scouting" for hunts. Speculating as to where to go and then actually going there and finding out if your "speculations" were correct is fun, not to mention it helps pass the time before those hunts. Of course, we don't always get it right with those speculations so it is always best to allow enough time to actually physically check things out if possible.