If the gun was being sighted in from a stable position, then it should be fine and wouldn't matter left or right handed. However, if the gun was sighted in from an unstable position (off hand), your sight adjustments could potentially be compensating for something unique to your shooting, such as a flinch. Test shoot from a lead sled, sand bag, etc to minimize shooter induced error, and then adjust your sights from that. Any problems now will be in the technique of the shooter.