I have never used an artificial blind,...and don't plan on ever doing so. Will that attitude change with advancing age and less mobility? Not sure,...we'll see,...but I honestly can't imagine that happening. Just not my bag, but others can have at it. Although it is rare around these parts, I occasionally see someone using a pop-up blind to hunt. I like that,...just means that I will not have to compete with that guy for that gobbling turkey that I am headed for.
Having said that, I have been in conditions where the skeeters and other flying critters were so bad that I probably would have jumped into a blind in a heartbeat if one had been available.