Most loads shoot to different POIs due to differing barrel harmonics, same as different rifle bullets do. With the wide patterns that conventional lead loads produce, it is often not readily apparent. But with the ultra-tight patterns produced by most HTL loads as well as Winch LBs, differences in POI become much more apparent. My best advice is pick the load you like based on its pattern and equip your gun with adjustable sights of some type. Then adjust POI to correspond to POA just like you would with a rifle and stick with that load.
