Regardless of which shoulder you normally shoot from, if you hunt long enough you'll have opposite shoulder shots presented. Last season I sat up for a right handed shot based on the last four gobblers that I'd taken from this big cottonwood tree on the point of a thicket; however, the gobbler came from my right making it necessary for me to shut my right eye forcing me to use my left eye as I squeezed the trigger with a left handed 40 yards shot. He flopped for a few minutes as I gathered my decoys. One deer season, I took a couple of does shooting from my left shoulder, utilizing a Horton knee pod to steady my H&R Ultra Slug Hunter. You might want to try a few left handed shots with a .22 to get used to the awkward feeling before moving up to a shotgun's recoil. Shooting from the opposite shoulder is not a hard thing to do, but it does feel uncomfortable. Just concentrate on the shot and it will probably work out.
