Not without taking the optic off first. Depending on the height of the rail you should be able to see you sights without taking them off. I have a supernova that had a weaver 423m base and I could see my sights fine. I changed to a little higher rail, picatinny .31 with a v cut and I can still see the sites. I got a blank picatinny and drilled the holes to fit and custom fit it so the optic could sit closer to my eye. But when I remove the optic I can still see my fiber optics. Not sure if this is what you're asking but I do believe you'll need to remove your optic but you'll be able to see your fiber optic sites with the base mount still on your gun.
Jeremiah 29:11